BOOK

Teiryo Teki Kozo Kassei Sokan Hansch Ho No Kiso to Oyo / Hara Title : EXPLORING QSAR : FUNDAMENTALS and APPLICATIONS in CHEMISTRY and BIOLOGY

C. Khan Shi / Cho a. Reo / Cho Ezaki Toshiyuki / Yaku

10000yen
(11000yen Tax incl. in Japan)
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Release Date February 09, 2014
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Product Details

Catalog No.NEOBK-1623596
JAN/ISBN 9784805208663
Product Type BOOK
Pages 563

Books are basically written in Japanese except for bilingual books or ones indicated as not written only in Japanese.

Translate Description

*As it is a machine translation, the result may not provide an accurate description. Please use it only as a reference. *Not available within the China mainland region.

Description in Japanese

定量的構造活性相関 Hansch法の基礎と応用 / 原タイトル:EXPLORING QSAR:FUNDAMENTALS AND APPLICATIONS IN CHEMISTRY AND BIOLOGY / C.ハンシュ/著 A.レオ/著 江崎俊之/訳

初心者でも容易に理解でき、かつ適用範囲が広いのが特徴である。基礎編では、Hansch法で使われる置換基定数のうち、σ定数、立体定数および分配係数などについて説明され、特に分配係数に関しては、フラグメント法による計算の概要も詳しく解説されている。また、応用編では、酵素‐リガンド相互作用、薬物代謝、抗腫瘍薬、中枢神経系作用薬、抗微生物薬、農薬(除草剤、殺虫剤)などへのQSARの応用が取り上げられている。

Related Offer & Feature

    Tracklisting

    1
    有機反応に及ぼす電子効果
    2
    Hammett式とその拡張形の応用
    3
    有機反応に及ぼす立体効果
    4
    疎水パラメータ:測定と計算
    5
    フラグメント法によるオクタノール‐水分配係数の計算
    6
    非特異的毒性のQSAR
    7
    蛋白質と酵素のQSAR
    8
    代謝のQSAR
    9
    変異誘発、発癌および抗腫瘍薬のQSAR
    10
    中枢神経系作用薬のQSAR〔ほか〕

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