Games Series Beginning with S
- Shuffle!
- Shugo Chara!
- Shy N Post
- Silent Hill
- Simakosaku Series
- Simoun
- SIMPLE 2000 Series
- SINoALICE
- Sister Princess
- Sk8
- Skate Leading Stars
- Sket Dance
- Skiing
- Skip Beat!
- Sky Crawlers
- Slayers
- Slow Start
- Smart
- Smile of the Arsnotoria
- smiley*2G Se Smiley Gakuen
- Smurf
- Snack World
- Snoopy
- Snowboard
- Soccer/Foot Ball
- Sonic the Hedgehog
- Sono Kisekae Ningyo wa Koi wo Suru
- Sora no Manimani
- Sora no Otoshimono
- Soranowoto
- Soredemo Ayumu wa Yosetekuru
- Sosei no Onmyoji (Twin Star Exorcists)
- Soul Eater
- Soul Link
- Souten no Ken
- South Park
- SPA!
- Space Channel 5
- Spec
- Spider-Man
- Splatoon
- Sponge Bob
- Spoon.
- SPRIGGAN
- SPY ROOM (Spy Kyoshitsu)
- SPY x FAMILY
- Stand My Heroes
- Star Driver Kagayaki no Takuto
- Star Ocean
- Star plus One
- Star Wars
- Star-Myu
- Starry Sky Series
- Steady.
- SteamBoy
- Steins; Gate
- Storm Lover
- Strawberry Panic
- Street Fighter
- Strike The Blood
- Studio Ghibli
- Sugar Bunnies
- Suika
- Suikoden Series
- Sukatto Golf Panya
- Suki desu Suzuki-kun
- Sukisho
- Sumikko Gurashi
- Summertime Render
- Summon Night
- Sumomo mo Momo mo
- SUPER LOVERS
- Super Mario Brothers
- Super Robot Taisen
- Super Sentai Series(Heroes)
- Super Soniko
- Supipara
- Switch
- Sword Art Online
- Sword World Series (RPG)
- SYNDUALITY
- The Disastrous Life of Saiki K.
- The invader comes from the bottom of the sea!Shinryaku! Ika Musume
- The Melancholy of Haruhi Suzumiya-chan (The Melancholy of Haruhi-chan Suzumiya) to Nyoron Churuya-san
- The Silver Mask
- The Thousand Noble Musketeers (Senjushi)
- World Break: Aria of Curse for a Holy Swordsman